Glucophage SR: An In-depth Overview

Glucophage SR, also known as Metformin Hydrochloride, is a widely prescribed medication used primarily for managing Type 2 diabetes. This extended-release formula helps in controlling blood glucose levels effectively. Understanding its mechanism, usage, and potential side effects is crucial for both patients and healthcare providers.

What is Glucophage SR?

Glucophage SR is an extended-release version of Metformin, a first-line therapy for Type 2 diabetes mellitus. It belongs to the biguanide class of drugs that help improve blood sugar control. Unlike immediate-release Metformin, Glucophage SR is designed to release the medication slowly, reducing gastrointestinal side effects and ensuring better compliance.

Mechanism of Action

Glucophage SR works by decreasing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization. By addressing these three pathways, it helps maintain stable blood sugar levels throughout the day.

Indications for Use

• Management of Type 2 Diabetes Mellitus
• Polycystic Ovary Syndrome (PCOS) in some cases
• Off-label uses include weight management and prevention of Type 2 diabetes in high-risk populations

How to Use Glucophage SR

Proper administration of Glucophage SR is vital for its effectiveness:

• Dosage: Typically, the starting dose is 500 mg once daily with the evening meal. The dose may be increased gradually to minimize gastrointestinal symptoms, with a maximum dose of 2000 mg per day.
• Administration: Swallow the tablet whole with water, do not crush or chew. It is best taken with a meal to reduce the risk of an upset stomach.

For a personalized dosage plan, it’s recommended to consult a healthcare professional. You can find detailed dosage information and purchase options on our website.

Possible Side Effects

While Glucophage SR is generally well-tolerated, some users may experience side effects:

• Gastrointestinal issues such as nausea, vomiting, diarrhea, and flatulence
• Lactic acidosis, though rare, is a serious side effect that requires immediate medical attention
• Vitamin B12 deficiency with long-term use

For a comprehensive list of side effects, consult your healthcare provider or refer to reputable medical resources.

Comments from Experts

“Glucophage SR has revolutionized the management of Type 2 diabetes by providing a more patient-friendly dosing option,” says Dr. Sarah Thompson, Endocrinologist. “Its extended-release formulation minimizes side effects, improving compliance and overall outcomes.”

“Patients on Glucophage SR should have regular follow-ups to monitor their HbA1c levels and renal function,” advises Pharmacist John Lee. “This ensures the medication is working effectively and safely.”

Additional Resources and Recommendations

For further reading on Glucophage SR, consider reviewing articles from reputable medical journals and government resources like the National Institutes of Health and FDA. These platforms provide valuable insights and the latest research findings.

If you’re considering Glucophage SR as part of your diabetes management plan, make sure to consult with your healthcare provider for personalized advice. Visit our website for more information on purchasing Glucophage SR and accessing support from our knowledgeable staff.